Related Experiment Video
Updated: Jun 12, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
Published on: July 20, 2022
Specialist pediatric dialysis nursing improves outcomes in children on chronic peritoneal dialysis
W D Vindya N Gunasekara1, Kar-Hui Ng, Yiong-Huak Chan
1Shaw-NKF Children's Kidney Centre, University Children's Medical Institute, National University Health System, Singapore, Singapore.
Insights
Establishing a dedicated pediatric dialysis nursing team significantly reduced peritonitis and exit site infection rates in children undergoing chronic peritoneal dialysis (PD). This specialist care improved PD outcomes by minimizing infection risks.
Area of Science:
- Nephrology
- Pediatric Nursing
- Dialysis Care
Background:
- Chronic peritoneal dialysis (PD) in children in Singapore began in 1988, initially managed by adult nurses.
- A specialized pediatric dialysis nursing team was introduced in 1998 to address specific needs.
Purpose of the Study:
- To evaluate the impact of nursing service models on PD-related outcomes in pediatric patients.
- To compare infection-related outcomes between periods managed by adult nurses versus a specialist pediatric nursing team.
Main Methods:
- Retrospective analysis comparing two nursing periods: adult nurses (1988-1998) and pediatric nurses (1998 onwards).
- Key outcomes assessed include peritonitis rates, exit site infection rates, and frequency of infections.
- Statistical analysis using relative risks (RR) and 95% confidence intervals (CI), adjusted for relevant factors.
Main Results:
- Higher rates of peritonitis (RR 1.90), exit site infections (RR 2.16), and peritonitis risk in the first year (RR 3.65) were observed under adult nursing care.
- Multiple peritonitis attacks were also more frequent in the adult nursing group (RR 2.45).
- Pediatric PD peritonitis rates remained high until the establishment of the specialist pediatric nursing team.
Conclusions:
- The establishment of a specialist pediatric dialysis nursing team significantly improved infection-related outcomes for children on chronic peritoneal dialysis.
- Specialized pediatric nursing care is crucial for optimizing the safety and effectiveness of PD in pediatric populations.
Abstract:
Chronic peritoneal dialysis (PD) for children in Singapore was instituted in 1988 at the National University Hospital with adult nurses providing dialysis services during the first 10 years. In 1998, a specialist pediatric dialysis nursing team was recruited. This study was conducted to determine the impact of dialysis nursing service on PD-related outcomes during the two nursing periods. Comparing the adult (group 1) and pediatric (group 2) nursing periods, the peritonitis rate was significantly higher in group 1 (RR 1.90; 95%CI 1.27-2.84), and this association did not weaken after adjusting for age, gender, and exit site infections. Exit site infection rate (RR 2.16; 95%CI 1.44-3.23), risk of peritonitis during the first year (RR 3.65; 95%CI 1.68-7.90), and multiple peritonitis attacks (RR 2.45; 95%CI 1.32-4.55) were higher in group 1. The peritonitis rates for adult patients cared for by the same adult nurses declined sharply from 1.05 episodes per patient-year between 1989 and 1992 to 0.41 episodes per patient-year between 1995 and 1997, however the corresponding pediatric rates did not change (1.48 to 1.06 episodes per patient-year, respectively) until the second era when specialized pediatric nurses were available. In conclusion, establishment of a specialist pediatric dialysis nursing team resulted in significant improvement in infection-related PD outcomes.
Related Concept Videos
Peritoneal Dialysis III: Nursing Management
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Peritoneal Dialysis I: Introduction and Procedure
Pharmacokinetics in Pediatric Patients: Drug Excretion
Acute Kidney Injury V: Interprofessional Care
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
