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Updated: Jun 12, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

Impella 2.5.

Daniel H Raess¹, David M Weber

¹Abiomed, Danvers, MA, USA. draess@abiomed.com

Journal of Cardiovascular Translational Research

|June 19, 2010

Summary

This summary is machine-generated.

The Impella 2.5 is a minimally invasive heart pump that supports systemic blood flow. Clinical trial results and general use are discussed.

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Area of Science:

Cardiovascular devices
Medical engineering
Hemodynamics

Background:

The Impella 2.5 is a percutaneous microaxial circulatory support pump.
It augments systemic blood flow by pumping directly from the left ventricle into the ascending aorta.

Purpose of the Study:

To describe the Impella 2.5 device.
To detail its insertion method and principles of action.
To present clinical results from the Protect I trial and general use.

Main Methods:

Device description and insertion technique.
Review of fundamental principles of action.
Analysis of clinical outcomes from the Protect I trial.
Summary of general use under FDA clearance.

Main Results:

The Impella 2.5 delivers up to 2.5 L/min of systemic flow.
Clinical results from the Protect I trial are presented.
General use information under FDA clearance is included.

Conclusions:

The Impella 2.5 is a percutaneous circulatory support device.
It offers systemic flow augmentation.
Clinical data and usage guidelines are provided.