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Updated: Jun 12, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Recurrent, severe, and rapidly reversible apical ballooning syndrome in status asthmaticus
Stephen L Rennyson1, Jeremy M Parker, John D Symanski
1Department of Internal Medicine, Carolinas Medical Center, Charlotte, North Carolina 28232, USA.
Abstract:
Apical ballooning syndrome, or Tako-tsubo cardiomyopathy, is a peculiar form of transient left-ventricular dysfunction originally described as triggered by emotional stress. Subsequent reports indicated that physical stressors can also induce this clinical syndrome. We describe for the first time, to the best of our knowledge, a case of recurrent, severe, and quickly reversible apical ballooning syndrome provoked by the use of high-dose inhaled β-adrenergic agonists in status asthmaticus.
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