Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 12, 2026

Voltage Biasing, Cyclic Voltammetry, & Electrical Impedance Spectroscopy for Neural Interfaces
07:51

Voltage Biasing, Cyclic Voltammetry, & Electrical Impedance Spectroscopy for Neural Interfaces

Published on: February 24, 2012

Current waveforms for neural stimulation-charge delivery with reduced maximum electrode voltage.

Mark Edward Halpern1, James Fallon

  • 1National Information and Communications Technologies Australia (NICTA) Victoria Research Laboratory (VRL), Department of Electrical and Electronic Engineering, University of Melbourne, Parkville,Vic. 3010, Australia. mark.halpern@nicta.com.au

IEEE Transactions on Bio-Medical Engineering
|June 22, 2010
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of gastric conduit electrophysiology in postesophagectomy patients using high-resolution body surface gastric mapping.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2026
Same author

Neural Gastric Electrical Stimulation: Future Prospects in Managing Gastric Emptying Disorders.

Journal of neurogastroenterology and motility·2026
Same author

An Educational Evaluation of Medical Students' Attitudes Towards Intellectual Disability.

The clinical teacher·2025
Same author

Ensemble responses of auditory midbrain neurons in the cat to speech stimuli at different signal-to-noise ratios.

Hearing research·2024
Same author

Teaching, assessment and best practice in undergraduate psychiatry education in the UK: cross-sectional survey.

BJPsych bulletin·2024
Same author

Towards non-invasive peripheral stimulation as a treatment for Parkinson's disease gait.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2023

This study introduces a stepped current waveform for electrical neural stimulation, reducing peak electrode voltage. This optimized signal design successfully delivers charge efficiently in both saline and neural tissue.

Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Electrical Engineering

Background:

  • Neural stimulation relies on electrical signals delivered through electrodes.
  • Minimizing peak electrode voltage is crucial for safe and effective neural stimulation.
  • Current stimulation methods often use constant current phases, which can lead to high voltage spikes.

Purpose of the Study:

  • To design electrical signals for neural stimulation that minimize peak electrode voltage.
  • To generalize constant current stimulation to a stepped current waveform.
  • To optimize charge delivery for neural stimulation applications.

Main Methods:

  • Generalization of constant current stimulation to a stepped current waveform.
  • Application of optimization techniques to determine current segment magnitudes.

More Related Videos

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures
08:32

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures

Published on: May 7, 2017

Related Experiment Videos

Last Updated: Jun 12, 2026

Voltage Biasing, Cyclic Voltammetry, & Electrical Impedance Spectroscopy for Neural Interfaces
07:51

Voltage Biasing, Cyclic Voltammetry, & Electrical Impedance Spectroscopy for Neural Interfaces

Published on: February 24, 2012

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures
08:32

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures

Published on: May 7, 2017

  • Utilizing linear dynamic system theory for signal design.
  • Minimizing maximum electrode voltage while ensuring specified charge transfer within a set time.

    • Main Results:

    • A novel stepped current waveform for neural stimulation was designed.
    • The method successfully minimized peak electrode voltage during charge delivery.
    • Experimental validation in saline and neural tissue confirmed the approach's efficacy.

    Conclusions:

    • The proposed stepped current waveform is an effective method for neural stimulation.
    • This technique offers a way to reduce peak electrode voltage, enhancing safety and efficiency.
    • The optimization approach provides a robust framework for designing neural stimulation signals.