Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Feedback synaptic interaction in the dragonfly ocellar retina.

A Klingman, R L Chappell

    The Journal of General Physiology
    |February 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Voltage- and Ligand-Gated Conductances of Bipolar Cells From the Skate Retina.

    The Biological bulletin·2018
    Same author

    Serotonin-Like Immunoreactivity Reveals Evidence for Centrifugal Fibers and a Distinctive Class of Amacrine Cell in the Skate Retina.

    The Biological bulletin·2018
    Same author

    Perforated Patch Recordings From Isolated Skate Bipolar Cells.

    The Biological bulletin·2018
    Same author

    Adolescents' response to nuclear threat: Before and after the chernobyl accident.

    Journal of youth and adolescence·2013
    Same author

    Psychoeducation: applications in community health education settings.

    International quarterly of community health education·2010
    Same author

    Zinc modulation of hemichannel currents in Xenopus oocytes.

    The Biological bulletin·2003
    Same journal

    Conformational changes upon pore blocker removal reveal conductive states of TMEM16A.

    The Journal of general physiology·2026
    Same journal

    On the mechanism of hypomagnesemia with treatment-resistant seizures caused by variants of the Na+,K+-ATPase α1 subunit (ATP1A1).

    The Journal of general physiology·2026
    Same journal

    Label-free real-time imaging of mitochondrial matrix volume changes and permeability transition in living cells.

    The Journal of general physiology·2026
    Same journal

    Differential regulation of β1-dependent voltage shifts and kinetic modulation by an extracellular glutamate in NaV1.6 VSDIV.

    The Journal of general physiology·2026
    Same journal

    Mechanistic insights into DCPIB inhibition of VRAC: Electrostatic control and binding plasticity.

    The Journal of general physiology·2026
    Same journal

    An epilepsy-associated KV3.1 potassium channel variant acts via dominant-positive effect.

    The Journal of general physiology·2026
    See all related articles

    Dragonfly ocellar nerve dendrite responses are modulated by neurotransmitters. Gamma-aminobutyric acid (GABA) enhances responses, suggesting a feedback mechanism for light intensity signaling.

    Area of Science:

    • Neuroscience
    • Insect Physiology
    • Sensory Systems

    Background:

    • The dragonfly ocellus, a simple eye, provides insights into neural processing.
    • Understanding the ocellar nerve dendrite's intracellular response is key to visual processing.

    Purpose of the Study:

    • To investigate the role of neurotransmitters in modulating the dragonfly ocellar nerve dendrite response.
    • To develop a model explaining synaptic feedback mechanisms in the ocellus.

    Main Methods:

    • Application of drugs including curare, picrotoxin, bicuculline, and gamma-aminobutyric acid (GABA).
    • Recording and analysis of intracellular responses of the ocellar nerve dendrite.
    • Development of a computational model for synaptic feedback.

    Related Experiment Videos

    Main Results:

    • Curare blocked the response; picrotoxin and bicuculline eliminated the 'off' overshoot.
    • Bicuculline reduced response size and sensitivity; GABA increased response size.
    • Evidence suggests acetylcholine as an inhibitory receptor transmitter and GABA as a facilitory feedback transmitter.

    Conclusions:

    • A synaptic feedback model involving GABA release in the dark enhances sensitivity to dim light.
    • The ocellar nerve dendrite's dark potential may result from a dynamic equilibrium.
    • This system efficiently signals changes in light intensity across a wide range.