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Recurrent conjunctival dermoid cyst with reactive lymphoid hyperplasia
Rebecca C Stacy1, Frederick A Jakobiec, Francis C Sutula
1Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02116, USA.
Ophthalmic Plastic and Reconstructive Surgery
|June 22, 2010
Summary
This case study details a recurrent conjunctival dermoid cyst. Immunohistochemistry helped distinguish it from follicular lymphoma, and it did not recur after 14 months.
Area of Science:
- Ophthalmology
- Dermatology
- Pathology
Background:
- Conjunctival dermoid cysts are rare tumors typically found in adults.
- Recurrence can occur, necessitating accurate diagnosis.
Observation:
- A case of recurrent conjunctival dermoid cyst with reactive lymphoid hyperplasia is presented.
- Immunohistochemical analysis was performed on the cyst wall.
Findings:
- The reactive lymphoid hyperplasia was demonstrated to be polyclonal.
- Follicular centers within the cyst wall were negative for Bcl-2.
- Positive staining for CD20, Bcl-6, CD10, and Ki67 differentiated the lesion from follicular lymphoma.
Implications:
- Accurate immunohistochemical evaluation is crucial for diagnosing conjunctival dermoid cysts.
- This case highlights the importance of differentiating these benign lesions from malignant lymphomas.
- The presented case showed no recurrence after a 14-month follow-up period.
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