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Synthesis, characterization, and in vitro cytotoxic effects of K4 [PtCl2ATP]
K K Nayak1, R Bhattacharyya, P Maity
1Department of Chemistry, Jadavpur University Calcutta, India.
Journal of Inorganic Biochemistry
|March 1, 1991
Abstract:
An antineoplastic agent, cis-K4 [PtCl2ATP] has been synthesized and characterized, using elemental analysis, solution conductance, thermoanalysis, infrared, NMR spectroscopy, and circular dichroism studies. The in vitro cytotoxic effect imparted by this compound on Dalton's Lymphoma cells has been assessed by Trypan blue dye exclusion method and 51Cr release assays.