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Role of laboratory in rapid diagnosis of atypical mumps

K E Vandana1, G Arunkumar, Indira Bairy

  • 1Department of Microbiology, Kasturba Medical College, Manipal, Udupi, Karnataka, India. vandanake@gmail.com

The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases
|June 22, 2010
PubMed

Insights

Many mumps virus infections lack typical symptoms, delaying diagnosis and increasing illness. Recognizing these atypical cases and using IgM antibody tests can aid diagnosis, particularly in unvaccinated populations.

Area of Science:

  • Virology
  • Epidemiology
  • Immunology

Background:

  • Mumps virus infections frequently present without parotitis, complicating diagnosis.
  • Atypical presentations lead to delayed diagnosis and increased patient morbidity.
  • Diagnostic challenges are pronounced in unvaccinated individuals, especially in developing nations.

Purpose of the Study:

  • To highlight the diagnostic challenges posed by atypical mumps virus presentations.
  • To emphasize the importance of recognizing non-parotid mumps infections.
  • To advocate for the use of serological tests in diagnosing mumps.

Main Methods:

  • Review of clinical presentations of mumps virus infections.
  • Analysis of diagnostic delays associated with atypical symptoms.
  • Evaluation of the utility of IgM-specific antibody detection.

Main Results:

  • A significant proportion of mumps cases do not exhibit parotitis.
  • Delayed diagnosis is common in patients with atypical mumps presentations.
  • Serological testing for IgM antibodies can resolve diagnostic uncertainty.

Conclusions:

  • Awareness of atypical mumps presentations is crucial for timely diagnosis.
  • IgM-specific antibody testing is a valuable tool for mumps diagnosis.
  • Improved diagnostic strategies are needed for unvaccinated populations in developing countries.

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