Related Experiment Video
Updated: Jun 12, 2026

Frame-by-Frame Video Analysis of Idiosyncratic Reach-to-Grasp Movements in Humans
Published on: January 15, 2018
Specific grasp characteristics of children with trisomy 21
Marianne Jover1, Catherine Ayoun, Catherine Berton
1Département de Psychologie Développementale et Différentielle, Centre PsyCLE, Université Aix Marseille 1, 29 Avenue Robert Schuman, Aix en Provence Cedex 1, France. marianne.jover@univ-provence.fr
Insights
Children with trisomy 21 exhibit distinct manual skills, using fewer fingers and unique grasps. These atypical traits persist throughout development, indicating a unique developmental trajectory.
Area of Science:
- Developmental Psychology
- Pediatrics
- Genetics
Background:
- Children with trisomy 21 (Down syndrome) often show differences in motor skills.
- Understanding manual skill development in this population is crucial for targeted interventions.
Purpose of the Study:
- To investigate the grasp characteristics and their developmental changes in children with trisomy 21.
- To compare manual skills of children with trisomy 21 to typically developing peers.
Main Methods:
- Assessed grasp patterns in 35 children with trisomy 21 (aged 4-18) during standardized manual tasks.
- Included grasping wooden blocks of varying sizes and tasks from the Movement Assessment Battery for Children.
- Compared findings with 35 age-matched typically developing children.
Main Results:
- Children with trisomy 21 consistently used fewer fingers across tasks.
- They exhibited specific grasp patterns, including extending non-engaged fingers.
- Some atypical grasp features diminished with age, while others remained consistent.
Conclusions:
- Manual skills in children with trisomy 21 represent an atypical developmental pattern, not merely a delay.
- These findings highlight the need to consider unique developmental trajectories in trisomy 21.
- Further research into perceptual-motor development in trisomy 21 is warranted.
Abstract:
Children with trisomy 21 display atypical manual skills that change to some extent during development. We examined grasp characteristics and their development in 35 children with trisomy 21, aged 4-18 years, who performed simple manual tasks (two manual tasks of the Movement Assessment Battery for Children, and grasping of five wooden blocks whose size was determined by their hand size). The age-matched comparison group included 35 typically developing children. Children with trisomy 21 were found to use fewer fingers than children in the comparison group in each task. They also used specific grasps and tended to extend fingers that were not involved in the grip. While some specific grasp characteristics of children with trisomy 21 decreased with age, other did not, and remained present throughout development. The perceptual-motor development of children with trisomy 21 should be analyzed in terms of atypical development rather than developmental delay.
Related Concept Videos
Meiosis I
Karyotyping
Nondisjunction
Nondisjunction

