Related Experiment Video
Updated: Jun 12, 2026
Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
Published on: January 12, 2020
[Level of CA125 and hemoglobin as prognostic factors ovarian cancer]
J Chovanec1, J Bienertová-Vasků, Z Dostálová
1Gynekologicko-porodnická klinika LF MU a FN, Brno.
Aim Of The Study:
Aim of the study was to investigate connection between the level CA125, level of haemoglobin and emergence of recurrence and survival time for patients with ovarian cancer.
Material And Methods:
This concerns of retrospective study in which total 53 patients with histology confirmed ovarian cancer were included. These patients were diagnosed and subsequently treated in the GPK FN MU Brno during 2000-2002 period.
Results:
The level of CA125 in our study appeared to be statistically significant prognostic factor (beta = 0.44, p = 0.02) for survival. Signification of the plasma level of haemoglobin to be any prognostic factor was not proved in this study. Among other assessed factors influencing survival time of the patients was the number of gravidity to be important prognostic factor (beta = -0.96, p = 0.002). Survival time was shorter for patients with less number of pregnancies.
Conclusion:
Ovarian cancer is tumour with high mortality. That is why it is necessary to look for new markers, which would contribute to earlier diagnostic of this disease, and which could influence its prognosis.
