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Updated: Jun 12, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
Enantioselective synthesis of planar chiral organonitrogen cycles
Katsuhiko Tomooka1, Kazuhiro Uehara, Rie Nishikawa
1Institute for Materials Chemistry and Engineering, Kyushu University, Kasuga, Fukuoka 816-8580, Japan. ktomooka@cm.kyushu-u.ac.jp
Abstract:
Enantioselective synthesis of a planar chiral organonitrogen cycle has been newly developed based on the unprecedented prochiral face-selective cyclization of achiral linear precursors by an appropriate chiral promoter.
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