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Related Experiment Video

Updated: Jun 12, 2026

An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach

An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach

Published on: December 7, 2016

Choroidal detachment after an uneventful intravitreal injection.

Carsten H Meyer¹, Christian K Brinkmann, Hans-Martin Helb

¹Department of Ophthalmology, University of Bonn, Bonn, Germany. meyer_eye@yahoo.com

Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics

|June 23, 2010

Summary

Choroidal detachment can occur after intravitreal injections, even without symptoms. This case study shows spontaneous resolution, highlighting the need to avoid injections in the same area until healed.

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Last Updated: Jun 12, 2026

An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach

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Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Published on: March 7, 2025

Area of Science:

Ophthalmology
Retinal diseases

Background:

Intravitreal injections are a common treatment for neovascular age-related macular degeneration.
Complications, though rare, can occur following these procedures.

Observation:

An 88-year-old patient developed an asymptomatic choroidal detachment post-intravitreal injection.
The detachment was located in the infero-temporal fundus.

Findings:

The choroidal detachment resolved spontaneously over a 6-month follow-up period.
Best corrected visual acuity improved significantly after subsequent injections in the contralateral quadrant.
No specific treatment was required for the choroidal detachment itself.

Implications:

Asymptomatic choroidal detachments are a potential complication of intravitreal injections.
Avoiding repeat injections in the same quadrant until resolution is advised to prevent exacerbation.