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Electron Behavior01:09

Electron Behavior

Electrons are negatively charged subatomic particles attracted to and orbit around the positively-charged nucleus of an atom. They reside in spaces associated with energy levels called shells and are further organized into subshells and orbitals within each shell.
Electrons Orbit the Nucleus
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Electron Behavior00:54

Electron Behavior

Electrons are negatively charged subatomic particles that are attracted to an orbit around the positively-charged nucleus of an atom. They reside in locations that are associated with energy levels called shells and are further organized into sub-shells and orbitals within each shell.Electrons Orbit the NucleusElectrons are found in specific locations outside of the nucleus. The shell in which an electron resides indicates the general energy level of the electron: those closer to the nucleus...
Enzyme-Linked Immunosorbent Assay01:33

Enzyme-Linked Immunosorbent Assay

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Direct Motor Pathways01:11

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New Features in Visual Dynamics 3.0
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Published on: August 9, 2024

EntrezAJAX: direct web browser access to the Entrez Programming Utilities.

Nicholas J Loman1, Mark J Pallen

  • 1Centre for Systems Biology, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. n.j.loman@bham.ac.uk.

Source Code for Biology and Medicine
|June 23, 2010
PubMed
Summary

EntrezAJAX enables web applications to access National Center for Biotechnology Information (NCBI) Entrez data, overcoming browser security limits. This tool simplifies integrating biomedical data into web resources.

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Area of Science:

  • Bioinformatics
  • Web Development
  • Biomedical Informatics

Background:

  • Web applications in biology and medicine require data integration from NCBI Entrez services.
  • Direct Entrez access from web browsers is restricted by same-origin security policies.
  • Asynchronous JavaScript and XML (AJAX) is widely used for interactive web applications.

Purpose of the Study:

  • To describe EntrezAJAX, a service enabling web applications to access Entrez eUtils.
  • To overcome same-origin security restrictions for accessing Entrez data via AJAX.
  • To facilitate the development of integrated biomedical web resources.

Main Methods:

  • Developed EntrezAJAX to provide access to Entrez eUtils.
  • Implemented a solution to circumvent same-origin browser restrictions.
  • Deployed EntrezAJAX on Google App Engine for scalability and reliability.

Main Results:

  • EntrezAJAX provides full Entrez eUtils functionality.
  • Offers enhanced features to simplify development for JavaScript developers.
  • Includes illustrative JavaScript examples for potential use cases.

Conclusions:

  • EntrezAJAX successfully enables AJAX access to Entrez services, overcoming security barriers.
  • The service simplifies the integration of biomedical data into web applications.
  • Its deployment on Google App Engine ensures speed, reliability, and scalability.