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Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium
Published on: August 7, 2015
[HIV retinal vasculitis].
P Drake-Casanova1, J Paz Moreno-Arrones, M Gorroño Echebarría
1Licenciada en Medicina, Universidad Autónoma de Madrid, Madrid, Spain. pilardrake@hotmail.com
Archivos De La Sociedad Espanola De Oftalmologia
|June 23, 2010
Summary
Untreated human immunodeficiency virus (HIV) can cause eye inflammation like retinal vasculitis. Prompt antiretroviral therapy effectively resolves these serious ocular complications in HIV patients.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Retinal Vasculitis
Background:
- Ocular complications are common in untreated human immunodeficiency virus (HIV) infections.
- Intraocular inflammation affects over half of untreated HIV patients, presenting various clinical manifestations.
Observation:
- A case report details a 47-year-old woman with a 5-year history of untreated HIV presenting with a left-eye floater.
- Peripheral retinal vasculitis was diagnosed and confirmed via angiography.
Findings:
- No specific infectious source was identified for the vasculitis.
- Treatment with antiretroviral therapy and corticosteroids led to complete resolution of the retinal vasculitis.
Implications:
- This case underscores that intraocular inflammation can be a direct consequence of HIV infection, not solely opportunistic infections or tumors.
- Antiretroviral therapy is crucial for managing HIV-associated ocular complications, highlighting the importance of timely treatment initiation.
