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Updated: Jun 12, 2026
Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma
Published on: January 12, 2024
[Primary cerebral lymphoma diagnosed by the ophthalmologist]
M Castro-Rebollo1, E N Vleming, P Drake-Rodríguez
1Licenciado en Medicina, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain. mariarebollo@yahoo.es
Case Report:
A 20-year-old male, HIV positive, with myodesopsias (floaters) in both eyes for two weeks. Fundus examination revealed bilateral papillary oedema with peripapilar flame-shaped haemorrhages. The neuroimaging tests showed a cerebral mass in the left parietal lobe. The biopsy confirmed the diagnosis of lymphoid neoplasm.
Discussion:
Primary lymphoma is the most common malignancy of the central nervous system (CNS) in AIDS patients, although highly active antiretroviral therapy has reduced its incidence. The ophthalmologist plays an essential role in the diagnosis of CNS neoplasm.