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ACE I/D genotype, habitual physical activity, and blood pressure in children
Mark A Sarzynski1, Joey C Eisenmann, Gregory J Welk
1Depts. of Kinesiology and Pediatrics and Human Development, Michigan State University, East Lansing, MI, USA.
Abstract:
The present study examined the association between the angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism, physical activity, and resting blood pressure (BP) in a sample of 132 children (48.4% female). Children attaining 60 min/day of moderate-to-vigorous physical activity (MVPA) possessed lower % body fat (29% vs 24%, p < .05). Resting BP did not significantly differ between genotypes. Furthermore, partial correlations between MVPA and BP were low and did not vary by ACE genotype. Thus, the ACE I/D genotype is not associated with BP and does not modify the relationship between physical activity and BP in this sample of children.
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