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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Updated: Jun 12, 2026

Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation
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Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation

Published on: December 30, 2025

Facial transplantation.

Maria Siemionow1, Yalcin Kulahci

  • 1Department of Plastic Surgery, The Cleveland Clinic, Cleveland, Ohio.

Seminars in Plastic Surgery
|June 23, 2010
PubMed
Summary
This summary is machine-generated.

Facial reconstruction aims to restore both appearance and function. Achieving both optimal aesthetic and functional outcomes in facial reconstruction remains a significant challenge.

Keywords:
Facial transplantationallotransplantationbioethicsreconstructive surgery

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Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer

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Last Updated: Jun 12, 2026

Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation
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Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
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Published on: March 1, 2015

Area of Science:

  • Plastic Surgery
  • Anatomy
  • Biomedical Engineering

Background:

  • The face is crucial for identity, communication, and emotional expression.
  • Facial functions include speech, vision, and nonverbal communication.
  • Reconstruction of the face is vital but complex.

Purpose of the Study:

  • To highlight the importance of facial reconstruction.
  • To discuss the challenges in achieving both functional and aesthetic outcomes.
  • To emphasize the need for integrated approaches in facial reconstruction.

Main Methods:

  • Review of current reconstructive techniques.
  • Analysis of functional and aesthetic requirements.
  • Discussion of anatomical and biomechanical considerations.

Main Results:

  • Facial reconstruction presents significant challenges.
  • Optimal reconstruction requires addressing both form and function.
  • Specialized facial units demand tailored reconstructive strategies.

Conclusions:

  • Full functional and aesthetic facial reconstruction is difficult.
  • Reconstruction must consider the dual roles of facial structures.
  • Further innovation is needed for comprehensive facial restoration.