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Fractures: Bone Repair

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...

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Related Experiment Video

Updated: Jun 12, 2026

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Published on: April 11, 2012

Reconstruction of osteomyelitis defects.

Paul Dinh¹, Brian K Hutchinson, Charalampos Zalavras

¹University of Southern California, Los Angeles County Medical Center, Los Angeles, California.

Seminars in Plastic Surgery

|June 23, 2010

Summary

Reconstructing large bone defects from osteomyelitis is difficult. Free vascularized fibular grafts offer a solution for significant bone and soft tissue loss, improving limb salvage outcomes.

Keywords:

Osteomyelitis osteocutaneous flaps skeletal defects vascularized fibular graft

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Published on: March 24, 2019

Area of Science:

Orthopedic Surgery
Regenerative Medicine
Bone Defect Reconstruction

Background:

Osteomyelitis often results in significant bone and soft tissue loss, complicating treatment.
Chronic osteomyelitis necessitates surgical debridement, frequently leading to large defects.
Non-vascularized bone grafts may fail in defects larger than 6 cm or those with poor healing potential.

Purpose of the Study:

To evaluate the efficacy of free vascularized bone grafts in reconstructing large skeletal defects.
To highlight the advantages of free vascularized fibular grafts for complex bone and soft tissue reconstruction.

Main Methods:

Utilizing free vascularized fibular grafts for skeletal reconstruction.
Transferring fibular grafts with accompanying soft tissues (skin, fascia, muscle) to address combined defects.

Main Results:

Free vascularized bone grafts are effective for skeletal defects exceeding 6 cm.
These grafts can also reconstruct smaller defects that have not healed with non-vascularized methods.
The fibular graft's characteristics (length, cortical strength, anatomy) make it ideal for bridging extremity defects.

Conclusions:

Free vascularized fibular grafts provide a reliable method for reconstructing large bone defects caused by osteomyelitis.
This technique effectively addresses both bone and associated soft tissue loss, crucial for limb salvage.
The versatility of the fibular graft allows for successful reconstruction in challenging orthopedic cases.