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Related Concept Videos

Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...

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Related Experiment Video

Updated: Jun 12, 2026

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model
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Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model

Published on: October 10, 2025

Multilevel cervical arthroplasty with artificial disc replacement.

Mario J Cardoso1, Michael K Rosner

  • 1Neurosurgery Service, Walter Reed Army Medical Center, Washington, DC 20307, USA. mtcardoso@comcast.net

Neurosurgical Focus
|June 24, 2010
PubMed
Summary
This summary is machine-generated.

Contiguous multilevel cervical disc arthroplasty using the Prestige ST artificial disc is a safe and effective alternative to fusion for treating cervical radiculopathy and myelopathy. This study details the surgical technique and positive outcomes in 10 patients.

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Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
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Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

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Last Updated: Jun 12, 2026

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model
07:06

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Published on: October 10, 2025

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
11:30

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Published on: July 25, 2025

Area of Science:

  • Neurosurgery
  • Orthopedic Surgery
  • Spinal Surgery

Background:

  • Cervical radiculopathy and myelopathy can necessitate surgical intervention.
  • Multilevel cervical disc arthroplasty is an emerging alternative to traditional fusion procedures.

Purpose of the Study:

  • To review the technique for contiguous multilevel cervical disc arthroplasty using the Prestige ST artificial disc.
  • To evaluate the safety and efficacy of this technique in patients with radiculopathy and myelopathy.

Main Methods:

  • Retrospective review of 10 patients who received contiguous Prestige ST implants for cervical disc arthroplasty.
  • Analysis of preoperative planning, surgical technique, and clinical/radiographic outcomes.
  • Patients had radiculopathy and/or myelopathy without prior cervical fusion.

Main Results:

  • Ten male patients (average age 45) underwent contiguous multilevel cervical disc arthroplasty with Prestige ST implants.
  • No cases of screw backout, implant dislodgment, progressive kyphosis, heterotopic bone, pseudarthrosis, or symptomatic adjacent level disease were observed.
  • Mean follow-up was 12 months, with positive clinical and radiographic results.

Conclusions:

  • Contiguous multilevel cervical disc arthroplasty with the Prestige ST is a safe and effective treatment option.
  • This technique offers a viable alternative to multilevel cervical arthrodesis (fusion).
  • The Prestige ST implant demonstrates favorable outcomes in managing complex cervical spine conditions.