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Updated: Jun 12, 2026
09:15
Stem Cell Transplantation in an in vitro Simulated Ischemia/Reperfusion Model
Published on: November 5, 2011
Developing a case study model for successful translation of stem cell therapies
Alan Trounson1, Elona Baum, Don Gibbons
1California Institute for Regenerative Medicine, San Francisco, CA 94107, USA. atrounson@cirm.ca.gov
Cell Stem Cell
|June 24, 2010
Summary
California is pioneering novel public-private partnerships to advance cell therapies from pluripotent stem cells. These "disease teams" aim to overcome regulatory hurdles for clinical translation.
Area of Science:
- Biomedical Science
- Regenerative Medicine
- Cell Therapy Development
Background:
- Pluripotent stem cell-derived therapies show promise but face significant translation challenges.
- Navigating complex regulatory pathways is a major barrier to clinical development.
Purpose of the Study:
- To introduce a novel framework for accelerating cell therapy translation.
- To facilitate the evaluation of new clinical opportunities within regulatory constraints.
Main Methods:
- Establishment of global public-private "disease team" partnerships.
- Collaborative approach involving diverse stakeholders to address translational barriers.
Main Results:
- A new model for partnership formation is proposed.
- The framework aims to streamline the evaluation of cell therapy candidates.
Conclusions:
- Public-private partnerships are crucial for overcoming cell therapy translation challenges.
- This initiative offers a strategic approach to navigate regulatory environments and advance clinical opportunities.
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