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Related Concept Videos

Blood Pressure01:24

Blood Pressure

The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
Blood Pressure01:30

Blood Pressure

Blood pressure (BP) is the pressure or force of blood exerted on the artery's walls as it circulates through the body. It is essential for maintaining blood flow throughout the body.
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the diastolic...
Sites for measuring blood pressure01:21

Sites for measuring blood pressure

Blood pressure measurement is a fundamental clinical procedure, providing crucial data for assessing cardiovascular health. Among the various sites for this measurement, the brachial and popliteal arteries are predominantly utilized due to their accessibility and the reliability of their readings. This lesson delves into the anatomical significance, methodology, and considerations of measuring blood pressure at these locations.
The Brachial Artery: Primary Site for Blood Pressure Measurement
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.
Assessment of blood pressure in brachial artery(two-step method)01:23

Assessment of blood pressure in brachial artery(two-step method)

Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...

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Related Experiment Video

Updated: Jun 12, 2026

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism
11:04

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Published on: September 1, 2014

Central aortic pressure is independently associated with diastolic function.

Sumeet Subherwal1, Lisa de las Fuentes, Alan D Waggoner

  • 1Duke University, Durham, NC, USA.

American Heart Journal
|June 24, 2010
PubMed
Summary
This summary is machine-generated.

Central aortic pulse pressure strongly associates with left ventricular (LV) filling pressure. Nonpulsatile aortic pressures show a weaker link to LV relaxation, impacting diastolic function assessment.

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Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice
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Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice

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Related Experiment Videos

Last Updated: Jun 12, 2026

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism
11:04

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Published on: September 1, 2014

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice
08:21

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice

Published on: June 15, 2020

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Physiology

Background:

  • Limited research exists on the relationship between central aortic pressures and diastolic function.
  • Understanding these associations is crucial for diagnosing and managing heart conditions.

Purpose of the Study:

  • To investigate the association between different components of central aortic pressure and measures of left ventricular (LV) diastolic function.
  • To determine which aspect of aortic afterload (pulsatile or nonpulsatile) is more influential on LV filling and relaxation.

Main Methods:

  • 281 patients with normal LV systolic function underwent assessment of LV filling pressure (E/Em) and relaxation (Em) using Doppler echocardiography.
  • Central aortic pressures, including systolic (cSBP), diastolic (cDBP), mean (cMAP), and pulse pressure (cPP), were measured via radial tonometry.
  • Stepwise linear regression models were used to analyze the associations between aortic pressures and diastolic parameters.

Main Results:

  • Central aortic pulse pressure (cPP) showed the strongest correlation with LV filling pressure (E/Em).
  • Nonpulsatile aortic pressures (cDBP and cMAP) had a significant but smaller association with LV relaxation (Em).
  • Multivariate analysis confirmed cPP as the primary contributor to E/Em, while cDBP and cMAP minimally contributed to Em.

Conclusions:

  • The pulsatile component of aortic afterload (cPP) is strongly linked to LV filling pressure.
  • Nonpulsatile aortic afterload components (cMAP, cDBP) are weakly associated with LV relaxation.
  • These findings highlight the importance of considering both pulsatile and nonpulsatile aspects of aortic pressure in evaluating diastolic function.