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Periprosthetic joint infection: the economic impact of methicillin-resistant infections

Javad Parvizi1, Ian M Pawasarat, Khalid A Azzam

  • 1Rothman Institute of Orthopedics at Thomas Jefferson University, Philadelphia, PA 19107, USA.

The Journal of Arthroplasty
|June 24, 2010
PubMed

Insights

Periprosthetic joint infections (PJIs) caused by resistant organisms are increasing and significantly more expensive to treat than those caused by sensitive strains. Implementing better prevention strategies is crucial to reduce the economic burden on orthopedics.

Area of Science:

  • Orthopedic surgery
  • Infectious disease
  • Health economics

Background:

  • Rising incidence of periprosthetic joint infections (PJIs)
  • Increasing prevalence of infections caused by antibiotic-resistant organisms

Purpose of the Study:

  • To investigate the economic impact of resistant organisms in PJIs
  • To compare treatment costs between PJIs caused by resistant and sensitive organisms

Main Methods:

  • Retrospective analysis of PJI treatment costs
  • Comparison of mean cost of care for infections caused by methicillin-resistant organisms versus sensitive strains

Main Results:

  • PJIs caused by methicillin-resistant organisms had a significantly higher mean cost of care ($107,264) compared to those caused by sensitive strains ($68,053)
  • P < .0001 indicates a statistically significant difference in treatment costs

Conclusions:

  • PJIs caused by resistant organisms represent a substantial economic burden on the healthcare system
  • There is a critical need for enhanced strategies to prevent the spread of resistant organisms in orthopedic settings
  • Addressing the economic and social impact of resistant PJIs is essential for the orthopedic community

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