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Related Concept Videos

Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

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Related Experiment Video

Updated: Jun 12, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
06:11

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

Published on: April 20, 2018

Anticancer oral therapy: emerging related issues.

Giuseppe Luigi Banna1, Elena Collovà, Vittorio Gebbia

  • 1Division of Medical Oncology, Vittorio Emanuele University Hospital, Via Plebiscito, 628, 95124 Catania, Italy. gbanna@yahoo.com

Cancer Treatment Reviews
|June 24, 2010
PubMed
Summary
This summary is machine-generated.

Oral anticancer drugs offer convenience and comparable efficacy to intravenous treatments. Patient compliance is key for optimizing oral cancer therapy outcomes and safety.

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Translationally-Relevant Tumor Resection Model for Murine Preclinical Models of Oral Squamous Cell Carcinoma
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Published on: April 20, 2018

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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Translationally-Relevant Tumor Resection Model for Murine Preclinical Models of Oral Squamous Cell Carcinoma
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Translationally-Relevant Tumor Resection Model for Murine Preclinical Models of Oral Squamous Cell Carcinoma

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Area of Science:

  • Oncology
  • Pharmacology
  • Patient Care

Background:

  • Increasing use of oral anticancer drugs driven by patient preference for home-based therapy.
  • Patients require equivalent efficacy and non-inferior toxicity compared to intravenous treatments.
  • Oncologists cite improved patient compliance, tolerability, convenience, and potential efficacy as reasons for preferring oral agents.

Purpose of the Study:

  • To review the advantages and considerations of oral anticancer drug administration.
  • To highlight the importance of patient compliance in oral cancer therapy.
  • To explore strategies for ensuring safe and effective oral anticancer treatment.

Main Methods:

  • Review of current evidence on oral versus intravenous anticancer therapy.
  • Analysis of factors influencing patient compliance with oral anticancer drugs.
  • Examination of pharmacokinetic considerations and patient-focused interventions.

Main Results:

  • Oral anticancer therapy demonstrates comparable quality of life to intravenous treatments.
  • Oral agents offer greater convenience, reduced work absence, and favorable cost-effectiveness.
  • Inter- and intra-individual pharmacokinetic variations are more significant for oral drugs.

Conclusions:

  • Patient selection, education, and accessible healthcare are crucial for successful oral therapy.
  • Home-care nursing interventions can support symptom management and compliance.
  • Oral anticancer drugs present a convenient, cost-effective, and effective treatment option when managed appropriately.