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Updated: Jun 12, 2026

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice
Published on: September 30, 2021
[Use of recombinant factor VII in Glanzmann thrombasthenia: a case report]
R Chabchoub Ben Abdallah1, L Trabelsi, S Ben Ameur
1Service pédiatrie, urgences et réanimation pédiatriques, CHU Hédi Chaker, Route El Ain Km 0.5, Sfax, Tunisia. rim.ben-abdallah@laposte.net
Abstract:
Glanzmann thrombasthenia (TG) is a congenital platelet function disorder characterized by frequent and occasionally severe bleeding events. Treatment is based on platelet transfusion at the time of bleeding. We report a case of GT revealed in the neonatal period, a severe hemorrhagic syndrome refractory to transfusions, treated at the age of 6 years. Activated recombinant factor VII (Novoseven) injections were necessary. The advantages of recombinant activated factor VII in GT patients with platelet antibodies and/or platelet transfusions refractoriness are discussed.
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