Related Experiment Video
Updated: Jun 12, 2026

12:55
A Microphysiological System to Study Leukocyte-Endothelial Cell Interaction during Inflammation
Published on: December 9, 2021
The microvacuolar system: how connective tissue sliding works
J C Guimberteau1, J P Delage, D A McGrouther
1Aquaitaine Hand Institute, Pessac, France. adf.guimberteau@wanadoo.fr
The Journal of Hand Surgery, European Volume
|June 24, 2010
Summary
This review clarifies the diverse roles of hand fascia, including its function in gliding and lubrication. Understanding this
Area of Science:
- Anatomy
- Biomechanics
- Hand Surgery
Background:
- The term 'fascia' encompasses diverse tissues in the hand, from strong ligaments to loose packing tissues.
- Traditional 'superficial' and 'deep' fascia classifications have limited applicability to the hand.
- Fascial functions include motion restraint, skin anchoring, and lubrication/gliding.
Purpose of the Study:
- To review the poorly described fascial tissues in the hand.
- To understand the structure and dynamic anatomy of hand fascia.
- To elucidate the 'microvacuolar system' for improved hand injury and disease outcomes.
Main Methods:
- Literature review focusing on fascial anatomy and function in the hand.
- Description of the 'microvacuolar system' as the sliding tissue of the hand.
Main Results:
- Hand fascia comprises tissues with distinct roles: motion restraint, skin anchoring, and lubrication.
- The 'microvacuolar system' facilitates tissue movement with minimal skin distortion and maintained continuity.
- Deep fascia is well-characterized, while other fascial components remain less understood.
Conclusions:
- A clearer understanding of hand fascial anatomy and its dynamic 'microvacuolar system' is crucial.
- This knowledge can enhance clinical outcomes for hand injuries and diseases.
- Further research into the poorly described fascial tissues is warranted.
Related Concept Videos
Overview of the Vascular System
The vascular system comprises an extensive network of arteries, capillaries, and veins. The vascular system can be broadly divided into the blood and lymphatic systems. Typically, blood vessels can be categorized into three histological regions: tunica intima, tunica media, and tunica adventitia. The tunica intima consists of a single layer of endothelial cells attached to the basal lamina. Underlying the basal lamina is a connective tissue layer and an elastic lamina that gives stability and...
Fluid Connective Tissues: Blood and Lymph
Blood and lymph are fluid connective tissues. They contain cells, also known as formed elements, circulating in a liquid extracellular matrix, the plasma. The formed elements are derived from hematopoietic stem cells in the bone marrow. Blood and lymph connect all vital parts and carry nutrients, oxygen, and other essential molecules like antibodies.
Blood
The blood flows through blood vessels— arteries, capillaries, and veins. Blood plasma is primarily made of proteins, solutes, and water.
Blood
The blood flows through blood vessels— arteries, capillaries, and veins. Blood plasma is primarily made of proteins, solutes, and water.
Functions of Connective Tissues
Connective tissues perform a broad range of functions in the body. Their primary function is to connect and link different tissues in the body and act as packaging material between tissues. The areolar tissue, a connective tissue prototype, commonly cements various tissue types in diverse body organs. In contrast, adipose tissue cushions internal organs while insulating the body from heat loss.
Hard connective tissues, such as bones and cartilage, provide structure and support to the body.
Hard connective tissues, such as bones and cartilage, provide structure and support to the body.
Structural Joints: Synovial Joints
Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
Layers of Connective Tissue Proper
Fascia, a thin layer of fibrous connective tissue, is distributed throughout the body. It demarcates and forms a supportive covering over skeletal muscles, bones, blood vessels, and organs. There are three main types of facia— superficial fascia, deep fascia, and subserous fascia. These are all present at different depths in the body. Fascia reduces the friction and permits muscles, joints, and organs to easily slide against each other, facilitating movement of the body and preventing tearing...
Introduction to Connective Tissues
Connective tissues are one of the four main tissue types in humans that are extensively present in the body. They are characterized by cells embedded in an extracellular matrix (ECM) composed of a ground substance and three main types of protein fibers— collagen, elastic, and reticular fibers. The ground substance of connective tissues can range from a watery and jelly-like consistency to mineralized and hard. The wide variety of cells in the connective tissues include fibroblasts, osteocytes,...

