Related Experiment Video
Updated: Jun 12, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Abnormal regional homogeneity of drug-naïve obsessive-compulsive patients
Tao Yang1, Yuqi Cheng, Haijun Li
1Department of Psychiatry, The First Affiliated Hospital of Kunming Medical College, Chinese Academy of Sciences, Kunming Institute of Zoology, The First Hospital of Kunming City, Kunming, China.
Abstract:
To explore the possible abnormal resting-state activity in patients with obsessive-compulsive disorder (OCD), the regional homogeneity (ReHo) of 22 pairs of patients and well-matched healthy controls was calculated. Compared with controls, the patients showed higher ReHo in the left anterior cingulate cortex, but lower ReHo in the left inferior temporal gyrus. These findings supported the abnormal resting-state brain activity in drug-naïve OCD patients. No significant correlations between ReHo value and four clinical characteristics were found, suggesting that abnormal ReHo might be trait-related in OCD.
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