Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices01:28

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...
Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs through the...
Drug Accumulation During Multiple Dosing: Repetitive IV Injections01:21

Drug Accumulation During Multiple Dosing: Repetitive IV Injections

Calculating drug dosage and accumulation in multiple-dose regimens is crucial for achieving therapeutic efficacy while avoiding toxicity. This involves determining the plasma drug concentrations over time to optimize dosing schedules. The principle of superposition is fundamental in this process, allowing for the prediction of drug concentration in plasma following multiple doses based on single-dose data.The principle of superposition asserts that the plasma concentration-time curves from...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tackling malnutrition in older people.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2017
Same author

Fresh focus on stroke care.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2017
Same author

Never had it so good.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2017
Same author

The high cost of cataracts.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2017
Same author

Nurses join pollution fight.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2016
Same author

Inside the fragile world of eating disorders.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2016

Related Experiment Video

Updated: Jun 12, 2026

A Novel Cell Injection Method with Minimum Invasion
06:24

A Novel Cell Injection Method with Minimum Invasion

Published on: April 21, 2023

Injection of support.

Catharine Sadler

    Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
    |June 25, 2010
    PubMed
    Summary

    The number of children with diabetic ketoacidosis arriving at A&E departments is increasing. Specialist nurses are crucial for supporting families and schools in managing childhood diabetes.

    Area of Science:

    • Pediatrics
    • Endocrinology
    • Public Health

    Background:

    • Rising incidence of pediatric diabetic ketoacidosis (DKA) presenting to emergency departments.
    • Increasing healthcare burden associated with managing DKA in children.
    • Need for improved support systems for families and educational institutions.

    Purpose of the Study:

    • To highlight the escalating trend of DKA in pediatric emergency care.
    • To underscore the necessity of specialized nursing support for diabetes management in children.
    • To advocate for enhanced resources for families and schools dealing with childhood diabetes.

    Main Methods:

    • Retrospective analysis of A&E attendance data for pediatric ketoacidosis.
    • Qualitative assessment of current support structures for diabetic children.

    More Related Videos

    Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction
    06:47

    Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction

    Published on: July 25, 2025

    Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury
    10:49

    Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury

    Published on: September 18, 2011

    Related Experiment Videos

    Last Updated: Jun 12, 2026

    A Novel Cell Injection Method with Minimum Invasion
    06:24

    A Novel Cell Injection Method with Minimum Invasion

    Published on: April 21, 2023

    Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction
    06:47

    Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction

    Published on: July 25, 2025

    Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury
    10:49

    Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury

    Published on: September 18, 2011

  • Literature review on effective diabetes management strategies.
  • Main Results:

    • Significant increase in pediatric ketoacidosis cases admitted through A&E.
    • Identified gaps in family and school-based diabetes education and management.
    • Correlation between inadequate support and higher DKA incidence.

    Conclusions:

    • Urgent need for increased pediatric diabetes nurse specialists.
    • Enhanced multidisciplinary approach required for comprehensive diabetes care.
    • Proactive management strategies are essential to reduce DKA prevalence in children.