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Updated: Jun 12, 2026

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect
Published on: September 22, 2023
Breastfeeding protects against adverse respiratory outcomes at 15 months of age
Karen M Silvers1, Chris M Frampton, Kristin Wickens
1Department of Medicine, University of Otago, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand. karen.silvers@xtra.co.nz
Insights
Breastfeeding significantly reduces the risk of respiratory issues like asthma and wheezing in infants. This study found a protective effect of breastfeeding on infant respiratory health up to 15 months of age.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- The link between breastfeeding and allergic diseases remains debated.
- Previous studies show mixed results regarding breastfeeding's impact on respiratory health and allergies.
Purpose of the Study:
- To examine the association between breastfeeding duration and respiratory outcomes, eczema, and atopy at 15 months.
- To investigate these relationships in a prospective birth cohort in New Zealand.
Main Methods:
- Prospective birth cohort study of 1105 infants, with 1011 followed to 15 months.
- Logistic regression analysis adjusted for confounders like ethnicity, socioeconomic status, and smoking in pregnancy.
- Assessment of breastfeeding duration, respiratory outcomes (asthma, wheezing, inhaler use), eczema, and atopy.
Main Results:
- Each month of exclusive breastfeeding reduced the risk of doctor-diagnosed asthma by 20%, wheezing by 12%, and inhaler use by 14%.
- Both exclusive and additional breastfeeding durations showed significant protective effects on respiratory outcomes.
- No association was found between breastfeeding and eczema or atopy at 15 months.
Conclusions:
- Breastfeeding demonstrates a significant protective effect against infant wheezing and other adverse respiratory outcomes.
- These respiratory outcomes may serve as early indicators for the development of asthma in children.
- The findings highlight the importance of breastfeeding for infant respiratory health in the New Zealand context.
Abstract:
The relationship between breastfeeding, respiratory and other allergic disorders has been controversial. Our aim was to investigate the relationships between breastfeeding, respiratory outcomes, eczema and atopy at 15 months of age in a prospective birth cohort in New Zealand. A total of 1105 children were enrolled at birth, and 1011 (91.2%) were followed up at 15 months. Logistic regression was used to model associations between breastfeeding duration and respiratory outcomes, eczema and atopy after adjusting for relevant confounding variables: ethnicity, socio-economic status, parity, body mass index, smoking in pregnancy, gender and respiratory infections in the first 3 months of life. Breastfeeding was associated with a significant reduction in the risk of adverse respiratory outcomes at 15 months. After adjustment for confounders, each month of exclusive breastfeeding reduced the risk of doctor-diagnosed asthma by 20% (odds ratio 0.80, 95% confidence interval 0.71 to 0.90), wheezing by 12% (0.88, 0.82 to 0.94) and inhaler use by 14% (0.86, 0.78 to 0.93). Associations for both exclusive and additional breastfeeding durations, and respiratory outcomes remained independently significant when modelled simultaneously. Although independently associated with all respiratory outcomes, adjusting for parental history of allergic disease or maternal history of asthma did not alter our findings. Breastfeeding was not associated with eczema or atopy at 15 months. In conclusion, there was a significant protective effect of breastfeeding on infant wheezing and other adverse respiratory outcomes that may be early indicators of asthma in New Zealand children.
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