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Updated: Jun 12, 2026

07:36
Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
[Borrelia-associated lymphocytoma cutis]
Summary
A 6-year-old boy developed Borrelia burgdorferi-associated lymphocytoma cutis on his ear. Prompt antibiotic therapy led to the lesion’s complete resolution, highlighting a favorable outcome for this benign B-cell process.
Area of Science:
- Dermatology
- Infectious Diseases
- Pediatrics
Background:
- Borrelia burgdorferi infection can manifest in the skin, presenting various clinical forms.
- Cutaneous lymphocytoma, a benign B-cell lymphoproliferative disorder, is a recognized manifestation of early disseminated Lyme disease.
- Distinguishing cutaneous lymphocytoma from malignant lymphomas is crucial for appropriate patient management.
Observation:
- A case study of a 6-year-old boy presenting with lymphocytoma cutis on the ear is detailed.
- The lesion was associated with Borrelia burgdorferi infection.
- Clinical presentation, physical examination, and serological tests were utilized for diagnosis.
Findings:
- The patient was diagnosed with Borrelia burgdorferi-associated lymphocytoma cutis.
- Histopathological analysis was considered for differential diagnosis with cutaneous lymphomas.
- The condition represents a subacute manifestation of early disseminated borrelial infection.
Implications:
- Early diagnosis and prompt antibiotic treatment are effective in resolving Borrelia burgdorferi-associated lymphocytoma cutis.
- The favorable prognosis of cutaneous lymphocytoma underscores the importance of accurate diagnosis in pediatric dermatology.
- This case reinforces the spectrum of cutaneous manifestations of Lyme disease and the efficacy of antimicrobial therapy.
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