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Related Concept Videos

Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
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Lymphoid Cells and Tissues

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Related Experiment Video

Updated: Jun 12, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

[Borrelia-associated lymphocytoma cutis].

C Palmen1, P Jamblin, B Florkin

  • 1Faculté de médecine, Ulg, Liège, Belgium.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|June 25, 2010
PubMed
Summary

A 6-year-old boy developed Borrelia burgdorferi-associated lymphocytoma cutis on his ear. Prompt antibiotic therapy led to the lesion’s complete resolution, highlighting a favorable outcome for this benign B-cell process.

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Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
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Published on: February 4, 2018

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Last Updated: Jun 12, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
07:20

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR

Published on: February 4, 2018

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Pediatrics

Background:

  • Borrelia burgdorferi infection can manifest in the skin, presenting various clinical forms.
  • Cutaneous lymphocytoma, a benign B-cell lymphoproliferative disorder, is a recognized manifestation of early disseminated Lyme disease.
  • Distinguishing cutaneous lymphocytoma from malignant lymphomas is crucial for appropriate patient management.

Observation:

  • A case study of a 6-year-old boy presenting with lymphocytoma cutis on the ear is detailed.
  • The lesion was associated with Borrelia burgdorferi infection.
  • Clinical presentation, physical examination, and serological tests were utilized for diagnosis.

Findings:

  • The patient was diagnosed with Borrelia burgdorferi-associated lymphocytoma cutis.
  • Histopathological analysis was considered for differential diagnosis with cutaneous lymphomas.
  • The condition represents a subacute manifestation of early disseminated borrelial infection.

Implications:

  • Early diagnosis and prompt antibiotic treatment are effective in resolving Borrelia burgdorferi-associated lymphocytoma cutis.
  • The favorable prognosis of cutaneous lymphocytoma underscores the importance of accurate diagnosis in pediatric dermatology.
  • This case reinforces the spectrum of cutaneous manifestations of Lyme disease and the efficacy of antimicrobial therapy.