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Fabricating and Labeling Microbubbles with Fluorescent and Radioactive Tracers

Fabricating and Labeling Microbubbles with Fluorescent and Radioactive Tracers

Published on: January 24, 2025

Microbubble Compositions, Properties and Biomedical Applications.

Shashank Sirsi¹, Mark Borden

¹Department of Chemical Engineering, Columbia University, 500 W 120 ST, New York, NY 10027.

Bubble Science Engineering and Technology

|June 25, 2010

Summary

Microbubbles are versatile theranostics, leveraging ultrasound responsiveness for advanced medical imaging and targeted drug delivery. Research explores diverse microbubble compositions for enhanced biomedical applications.

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Area of Science:

Biomedical Engineering
Nanotechnology
Materials Science

Background:

Microbubbles have emerged as key theranostic agents over the past decade.
Their ultrasound responsiveness enables applications in imaging and drug/gene delivery.

Purpose of the Study:

To review the progress in developing microbubbles for biomedical applications.
To discuss various microbubble compositions and their properties for molecular imaging and targeted delivery.

Main Methods:

Literature review of microbubble development and applications.
Analysis of different shell materials (proteins, lipids, polymers) and their impact.

Main Results:

Microbubbles offer tailored advantages based on their composition.
Significant advancements have been made in utilizing microbubbles for targeted therapies.

Conclusions:

Microbubble technology is rapidly advancing for sophisticated biomedical uses.
Further research into composition and properties will enhance their theranostic potential.