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Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running
Published on: July 17, 2020
Association between the angiotensin I-converting enzyme gene insertion/deletion polymorphism and endurance running
Takuro Tobina1, Ryoma Michishita, Fumihiro Yamasawa
1Graduate School of Sports and Health Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 810-0180, Japan. tobitaku@ck9.so-net.ne.jp
Abstract:
We investigated the association between the angiotensin I-converting enzyme (ACE) gene insertion (I)/deletion (D) polymorphism and endurance running performance in Japanese elite runners, including several Olympic athletes. The frequency of the I/I genotype was not significantly higher and the frequency of the D/D genotype was not significantly lower in elite runners compared with non-athletes. However, the frequency of the I/D genotype tended to be lower in elite runners than in non-athletes. The best performance was significantly higher for runners with the D/D genotype than for those with the I/I genotype, and the average running speed was significantly higher for those with the combined D/D + I/D genotypes than for those with the I/I genotype. There were no I/I genotypes among the five fastest marathon runners. These results suggest that the D allele of the ACE gene I/D polymorphism is associated with a high level of human endurance.
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