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[Process comparison of fingerprints of different extracts of Plumbago zeylanica by high performance liquid
Jia-hui Hu1, Li Gao, Xiao-ming Peng
1Pharmacy College of ShiHeZi University, Shihezi 832003, China. candy1baby1@yeah.net
Objective:
To optimize the separation conditions of fingerprints of Plumbago zeylanica by high performance liquid chromatography, on this basis, to choose the best way for extracting Plumbago zeylanica by high performance liquid chromatography.
Methods:
The investigation of HPLC-FPs of the different extraction samples was by the retention time and the relative area of common peaks in fingerprints.
Results:
We established the optimum separation conditions of HPLC-FPs for Plumbago zeylanica and there were 4 common peaks in fingerprints. According to the contrast research, the HPLC-FPs of the 90% ethanol extraction and SBE extraction of Plumbago zeylanica were quite similar, and they both had 9 common peaks in fingerprints, It was better to use SBE rather than WE in the extraction of Plumbago zeylanica.
Conclusion:
The SBE may replace the WE and ethanol extraction of Plumbago zeylanica.
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