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Glutathione S-transferase polymorphisms in osteosarcoma patients.

Carolina Salinas-Souza1, Antonio S Petrilli, Silvia R C de Toledo

  • 1Department of Pediatrics, Pediatric Oncology Institute (IOP/GRAACC/UNIFESP), Genetics Laboratory, Federal University of São Paulo, São Paulo, Brazil.

Pharmacogenetics and Genomics
|June 26, 2010
PubMed
Summary

Glutathione S-transferase (GST) gene polymorphisms influence osteosarcoma outcomes. Specific GSTM1 and GSTT1 genotypes correlate with treatment response, survival, and metastasis risk in osteosarcoma patients.

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