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[Cerebral sinus vein thrombosis in Behçet's disease]
H Borer1, S Rüttimann, C Kätterer
1Medizinische Universitäts-Poliklinik, Departement Innere Medizin, Kantonsspital Basel.
Schweizerische Medizinische Wochenschrift
|May 25, 1991
Summary
Superior sagittal sinus thrombosis can be an early sign of Behçet's disease, particularly in young men. Early anticoagulation and immunosuppressive therapy improve outcomes for this rare but serious neurological manifestation.
Area of Science:
- Neurology
- Rheumatology
- Vascular Medicine
Background:
- Cerebral venous thrombosis (CVT) is an underdiagnosed condition.
- Behçet's disease is a multisystem inflammatory disorder.
- CVT can be the initial presentation of Behçet's disease, even without typical symptoms like uveitis.
Observation:
- A 20-year-old patient presented with superior sagittal sinus thrombosis.
- This led to a diagnosis of Behçet's disease.
- Uveitis, a key diagnostic criterion, was absent in this case.
Findings:
- Cerebral venous thrombosis should be considered in patients with intracranial hypertension, especially in high-risk populations.
- Behçet's disease may manifest initially as CVT.
- Early diagnosis and treatment are crucial for favorable prognosis.
Implications:
- Highlights the importance of considering Behçet's disease in unexplained CVT.
- Suggests a need for increased awareness of CVT as an early sign of Behçet's disease.
- Emphasizes timely anticoagulation for CVT and immunosuppressive therapy (e.g., corticosteroids, azathioprine, cyclosporin A) for Behçet's disease.