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Related Concept Videos

Immunogold Electron Microscopy01:20

Immunogold Electron Microscopy

Immunoelectron microscopy utilizes immunogold labeling of endogenous proteins with specific antibodies to detect and localize these proteins in cells and tissues. The procedure provides insights into the distribution and quantification of protein under different stimulation conditions offering clues about their functions. Conjugating highly electron-dense gold particles with primary or secondary antibodies allow antigen detection on and within cells, with high resolution and specificity.
Gas Chromatography: Types of Detectors-II01:19

Gas Chromatography: Types of Detectors-II

In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized...

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Related Experiment Video

Updated: Jun 12, 2026

Detection and Recovery of Palladium, Gold and Cobalt Metals from the Urban Mine Using Novel Sensors/Adsorbents Designated with Nanoscale Wagon-wheel-shaped Pores
10:31

Detection and Recovery of Palladium, Gold and Cobalt Metals from the Urban Mine Using Novel Sensors/Adsorbents Designated with Nanoscale Wagon-wheel-shaped Pores

Published on: December 6, 2015

Mercury(ii) detection by SERS based on a single gold microshell.

Donghoon Han1, Sung Yul Lim, Beom Jin Kim

  • 1Department of Chemistry, Seoul National University, Seoul, 151-747, Korea.

Chemical Communications (Cambridge, England)
|June 26, 2010
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel method for detecting mercury ions (Hg2+) using DNA-modified gold microspheres. These microspheres serve as tiny SERS probes for precise analysis in minimal sample volumes.

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An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium
09:33

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium

Published on: December 17, 2018

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Last Updated: Jun 12, 2026

Detection and Recovery of Palladium, Gold and Cobalt Metals from the Urban Mine Using Novel Sensors/Adsorbents Designated with Nanoscale Wagon-wheel-shaped Pores
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Published on: December 6, 2015

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium
09:33

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium

Published on: December 17, 2018

Area of Science:

  • Nanotechnology
  • Analytical Chemistry
  • Biotechnology

Background:

  • Mercury ions (Hg2+) pose significant environmental and health risks.
  • Sensitive and selective detection methods for Hg2+ are crucial for monitoring and remediation.
  • Existing detection techniques may lack the required sensitivity or selectivity for trace analysis.

Purpose of the Study:

  • To develop a novel, highly sensitive, and selective method for Hg2+ detection.
  • To utilize DNA-modified gold microspheres as micro SERS probes.
  • To enable analysis in small sample volumes.

Main Methods:

  • Fabrication of gold microshells functionalized with DNA.
  • Individual manipulation of microspheres using a micropipette.
  • Utilizing Surface-Enhanced Raman Spectroscopy (SERS) for detection.

Main Results:

  • Demonstrated sensitive and selective detection of Hg2+ ions.
  • Showcased the capability of DNA-modified gold microspheres as micro SERS probes.
  • Validated the method's effectiveness in small sample volumes.

Conclusions:

  • The developed method offers a unique approach for Hg2+ detection.
  • DNA-modified gold microspheres are effective micro SERS probes for trace metal analysis.
  • This technique holds promise for environmental monitoring and diagnostics.