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Published on: February 2, 2024
Study of constituents of Veronicastrum villosulum
Toshihiro Nohara1, Ai Nakano, Mona El-Aasr
1Faculty of Pharmaceutical Sciences, Sojo University, 22-1, 4-chome, Ikeda, Kumamoto, 860-0082, Japan. none@ph.sojo-u.ac.jp
Abstract:
We investigated the constituents of Veronicastrum villosulum (Miquel) Yamazaki (Scrophulariaceae), an endangered species belonging to the IA group. From the aerial parts of this plant cultivated at the botanical garden of Sojo University, we isolated two new cucurbitacine-type glycosides, 3-O-alpha-L-rhamnopyranosyl-(1 --> 2)-[beta-D-glucopyranosyl-(1 --> 3)]-beta-D-glucopyranosides of 3beta,25-dihydroxycucurbit-5,23(E)-diene-7-one-25-methyl ether and 3beta,23-dihydroxycucurbit-5,24-diene-7-one-23-methyl ether.
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