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Updated: Jun 12, 2026
Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
Published on: February 16, 2024
Clinicopathologic characteristics and prognosis of mucinous gastric carcinoma
Ming Zhang1, Guan-yu Zhu, Hong-feng Zhang
1Department of Gastroenterologic Surgery, Affiliated Tumor Hospital of Harbin Medical University, Harbin, China.
Background And Objectives:
Reports of clinicopathological features and prognosis in patients with mucinous gastric carcinoma (MGC) are conflicting. The aim was to describe the clinicopathological features and prognosis of patients with MGC in comparison with nonmucinous gastric carcinoma (NMGC).
Methods:
We reviewed the records of 1,278 consecutive patients diagnosed with gastric carcinoma who were resected surgically from 1993 to 2003. Among them, 48 patients (3.8%) with MGC were compared to 1,230 patients with NMGC.
Results:
There were significant differences in tumor location, stage of disease, lymphatic invasion, and vascular invasion between the patients with MGC and NMGC. The overall 5-year survival of patients with MGC was 27.2% as compared with 42.8% for patients with NMGC (P = 0.031). For the patients with the same stage, there was no significant difference between MGC and NMGC. With respect to patients with MGC, multivariate analysis showed that lymph node metastasis and curative resection were significant factors affecting survival.
Conclusions:
MGC is rare and detected mostly in an advanced stage. Mucinous histology type itself is not an independent prognostic factor.
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