Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Alzheimer Disease ll: Pathophysiology01:23

Alzheimer Disease ll: Pathophysiology

Alzheimer disease involves structural changes in the brain that begin long before symptoms appear. The most distinctive features are extracellular neuritic plaques and intracellular neurofibrillary tangles.Neuritic plaques form in the cerebral cortex and around blood vessels. These plaques contain a dense core of beta-amyloid (Aβ)—a toxic protein fragment that clumps outside neurons. The core is surrounded by damaged neuronal extensions, as well as reactive astrocytes and microglia. Abnormal...
Muscles of the Vertebral Column01:27

Muscles of the Vertebral Column

The back muscles that lie deep into the thoracolumbar fascia are called intrinsic or true back muscles. These muscles are divided into four layers: superficial, intermediate, deep, and deepest layers.
Superficial Layer:
The superficial layer consists primarily of the splenius muscles, which include the splenius capitis and splenius cervicis. These muscles are mainly responsible for the head and cervical spine movements, including extension, rotation, and lateral bending. The splenius capitis...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Vertebral Column: Regions and Curvature01:16

Vertebral Column: Regions and Curvature

The vertebral column or spine is a flexible column that supports the head, neck, and body and  allows for their movements. It also protects the spinal cord.
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biologic Therapies for Severe Asthma: Current Insights and Future Directions.

Journal of clinical medicine·2025
Same author

Pemphigus vulgaris Treated With Rituximab: A Case Report.

Cureus·2024
Same author

Ulcerated Papulonodules in Crohn Disease: Answer.

The American Journal of dermatopathology·2024
Same author

Ulcerated Papulonodules in Crohn Disease: Challenge.

The American Journal of dermatopathology·2024
Same author

Cost-effectiveness of lung cancer screening with volume computed tomography in Portugal.

Journal of comparative effectiveness research·2024
Same author

Oncologic Emergencies in Lung Cancer Patients and the Effects of SARS-COV2 Pandemic.

Tanaffos·2024

Related Experiment Video

Updated: Jun 12, 2026

Urokinase-type Plasminogen Activator-induced Mouse Back Pain Model
06:20

Urokinase-type Plasminogen Activator-induced Mouse Back Pain Model

Published on: September 1, 2023

Brown plaques on the lower back.

Tiago Esteves1, Lurdes Ferreira, Isabel Viana

  • 1Hospital Central do Funchal, Funchal, Madeira, Portugal. tiago.castroesteves@gmail.com

Dermatology Online Journal
|June 29, 2010
PubMed
Summary
This summary is machine-generated.

A rare skin condition, Mucinous Nevus, presented as brown papules on a young girl's back. Histopathology confirmed mucin deposition in the dermis, aiding diagnosis.

More Related Videos

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
05:12

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

Related Experiment Videos

Last Updated: Jun 12, 2026

Urokinase-type Plasminogen Activator-induced Mouse Back Pain Model
06:20

Urokinase-type Plasminogen Activator-induced Mouse Back Pain Model

Published on: September 1, 2023

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
05:12

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

Area of Science:

  • Dermatology
  • Histopathology

Background:

  • Mucinous Nevus is a rare benign skin neoplasm.
  • Often presents in childhood or adolescence.
  • Characterized by mucin accumulation in the dermis.

Observation:

  • A 12-year-old girl presented with a 2-year history of asymptomatic, linearly arranged brown papules coalescing into plaques on her lower back.
  • No other physical or systemic abnormalities were noted.
  • Routine laboratory tests, including thyroid function, were within normal limits.

Findings:

  • Histopathological examination revealed epidermal changes such as hyperkeratosis, papillomatosis, and elongated rete ridges.
  • Special Alcian blue staining demonstrated significant mucin deposition in the papillary dermis.
  • The remaining dermal tissue appeared normal.

Implications:

  • This case highlights the characteristic histopathological features of Mucinous Nevus.
  • Accurate diagnosis relies on correlating clinical presentation with histopathological findings.
  • Understanding mucin deposition is key to differentiating Mucinous Nevus from other dermal conditions.