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Related Experiment Video

Updated: Jun 11, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

Breast augmentation: Part II--Adverse capsular contracture.

M G Berry¹, V Cucchiara, D M Davies

¹Institute of Cosmetic and Reconstructive Surgery, 1 Parkside, London W6 OUU, UK. enquiries@aestheticus.co.uk

Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS

|June 29, 2010

Summary

Adverse capsular contracture (ACC) after breast augmentation is a persistent challenge. Future research in immunology and molecular biology may lead to non-surgical prevention and treatment options for ACC.

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Last Updated: Jun 11, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

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Anterior Capsular Reconstruction with Human Dermal Allograft for Irreparable Subscapularis Tears

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Published on: May 9, 2025

Area of Science:

Plastic Surgery
Immunology
Molecular Biology

Background:

Adverse capsular contracture (ACC) remains a significant complication following breast augmentation.
Despite past progress, ACC is expected to persist due to increasing augmentation rates.
The focus of breast augmentation is shifting from preventing ACC to achieving aesthetic outcomes.

Purpose of the Study:

To review current knowledge on the aetiopathology of ACC.
To summarize existing evidence and expert consensus on ACC.
To guide the selection of appropriate therapeutic strategies for ACC.

Main Methods:

Literature review of clinical research on ACC.
Integration of findings from immunology and molecular biology.
Synthesis of evidence and consensus for aetiopathology and treatment.

Main Results:

ACC understanding has advanced, but it remains a challenge.
Clinical research has informed current prevention strategies.
New insights from immunology and molecular biology show promise.

Conclusions:

A comprehensive understanding of ACC aetiopathology is crucial.
Current strategies aim to manage and prevent ACC.
Future research may yield non-surgical treatments for ACC.