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Updated: Jun 11, 2026

Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse
03:43

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Published on: September 13, 2022

Gestational age at previous preterm birth does not affect cerclage efficacy.

Deborah A Wing1, Jeff Szychowski, John Owen

  • 1Department of Obstetrics and Gynecology, University of California, Irvine, Irvine, CA, USA.

American Journal of Obstetrics and Gynecology
|June 29, 2010
PubMed
Summary

Earlier spontaneous preterm birth (SPTB) is linked to shorter cervical length in subsequent pregnancies. However, ultrasound-indicated cerclage does not appear to offer greater benefit for women with earlier SPTB history.

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Area of Science:

  • Maternal-Fetal Medicine
  • Perinatal Research
  • Obstetrics and Gynecology

Background:

  • Spontaneous preterm birth (SPTB) is a significant concern in obstetric care.
  • Cervical length is a key predictor of preterm birth risk.
  • Ultrasound-indicated cerclage is used to prevent preterm birth in high-risk pregnancies.

Purpose of the Study:

  • To investigate the relationship between the gestational age of a prior SPTB and cervical length in a subsequent pregnancy.
  • To assess how the timing of a previous SPTB influences the efficacy of ultrasound-indicated cerclage.

Main Methods:

  • Secondary analysis of a randomized trial involving women with a mid-trimester cervical length <25 mm.
  • Included women with at least one prior SPTB between 17 and 33 weeks 6 days of gestation.
  • Serial ultrasounds were performed from 16 to 23 weeks 6 days; cervical length at randomization was analyzed.

Main Results:

  • A significant correlation was found between the gestational age of the previous SPTB and the qualifying cervical length (P = .0008).
  • In regression models, neither the previous SPTB gestational age nor its interaction with cerclage predicted subsequent birth gestational age when controlled for cervical length and cerclage.

Conclusions:

  • While earlier SPTB is associated with shorter cervical length in women with a mid-trimester cervix <25 mm, cerclage efficacy does not appear to be disproportionately enhanced.
  • These findings suggest that the benefit of cerclage may not be greater in women with a history of earlier preterm birth.