Age-stratified outcomes in elderly patients undergoing open and endovascular procedures for aortoiliac occlusive
Jeffrey E Indes1, Charles T Tuggle, Anant Mandawat
1Department of Surgery, Yale University School of Medicine, New Haven, CT 06510, USA. jeffrey.indes@yale.edu
Insights
For elderly patients with aortoiliac occlusive disease (AIOD), endovascular treatment offers better outcomes than open procedures, especially for those aged 70 and older. This approach reduces complications, hospital stay, and costs.
Area of Science:
- Vascular Surgery
- Geriatric Medicine
- Health Economics
Background:
- Elderly patients represent a significant population affected by aortoiliac occlusive disease (AIOD).
- Analysis of outcomes in elderly patients undergoing open and endovascular procedures for AIOD is crucial for optimizing care.
Purpose of the Study:
- To compare the clinical and economic outcomes of open versus endovascular procedures for AIOD in elderly patients.
- To stratify outcomes based on age groups within the elderly population.
Main Methods:
- Retrospective analysis of elderly AIOD patients from the HCUP-NIS database (2004-2007).
- Stratification into age groups: 65-69, 70-79, and 80+ years.
- Comparison using chi(2), ANOVA, and multivariate regression for complications, mortality, duration of stay, and hospital cost.
Main Results:
- Patients aged 80+ had higher rates of nonelective admissions, comorbidities, and iliac artery disease.
- Open procedures in the 80+ group showed higher complication and mortality rates.
- Endovascular procedures consistently demonstrated lower complication rates, shorter hospital stays, and reduced costs across all age groups.
- Mortality was significantly lower with endovascular treatment in patients aged 70+.
Conclusions:
- Clinical outcomes for both open and endovascular procedures for AIOD deteriorate with increasing patient age.
- Endovascular treatment is associated with a lower complication rate compared to open repair in patients aged 70 years and older.
Background:
The elderly comprise a sizeable segment of patients with aortoiliac occlusive disease (AIOD). We analyzed outcomes in elderly patients who underwent open and endovascular procedures for AIOD.
Methods:
Elderly patients with AIOD who underwent open and endovascular procedures in the Healthcare Cost and Utilization Project Nationwide Inpatient Sample (HCUP-NIS) database from 2004 to 2007 were identified. Patients were stratified into age groups: 65-69 years, 70-79 years, and 80 years or older. The clinical outcomes were complications and mortality; the economic outcomes were duration of stay and hospital cost. Both open and endovascular procedures were compared using chi(2) analysis, analysis of variance (ANOVA), and multivariate linear and logistic regression.
Results:
Patients aged 80 years or older were more likely be nonelective admissions (43%), have a high Charlson Comorbidity Index (12%), and have iliac artery disease (63%, all P < .05). Patients aged 80 years or older who underwent open procedures had higher complication and mortality rates compared with younger patients (both P < .05). Endovascular procedures had a lower complication rate, duration of stay, and hospital cost for all age groups (P < .05). Mortality was significantly lower for endovascular treatment in patients aged 70 years or older (P < .05). A multivariate analysis showed patients aged 70 years or older were at increased risk of complications (P < .05).
Conclusion:
For both procedures, clinical outcomes worsen as patient age increases. In patients aged 70 years or older, endovascular treatment conferred a lower complication rate than open repair.
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