Principles and recent developments in ultrasound contrast agents
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N de Jong1, F J Ten Cate, C T Lancée
1Thoraxcenter, Erasmus University Rotterdam, The Netherlands.
Ultrasonics
|July 1, 1991
Abstract:
The behaviour of gas bubbles and gas encapsulated spheres as echographic contrast agents is reviewed. Compared with rigid spheres, gas bubbles are superior scattering agents and they offer a number of useful properties which can be exploited in a variety of ways. The analysis of their velocity of sound, back-scatter intensity, second harmonic emission and resonant frequency opens up new perspectives in the development of contrast agents for echocardiographic research with potential clinical applications.