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Related Concept Videos

Introduction to force01:25

Introduction to force

Consider water flowing from a nozzle to a turbine vane. As the water hits the turbine vane, it exerts a force that causes it to move along the flow of direction. Force is an impact that changes an object's motion, shape, or orientation. Forces can be caused by physical contact, such as a push or pull, or through non-contact interactions, such as magnetic or gravitational forces. Force is a vector quantity with both magnitude and direction, and is measured in newtons (N) in the SI unit system.
An Introduction to Mechanics01:28

An Introduction to Mechanics

Humans have been making ships, shelters, pyramids, weapons, agricultural equipment, and many more items without recording the process or theory behind them for centuries. It would be challenging to document the evolution of mechanics from its origin to the present.
According to records, the history of mechanics starts with Aristotle (384–322 BC). He related mechanics to physical theory, aiming for a universal synthesis.
Newton defined mechanics as the branch of physical science that studies the...
Newton's First Law: Introduction01:17

Newton's First Law: Introduction

Motion draws our attention. Motion itself can be beautiful, causing us to marvel at the forces needed to create spectacular sights, such as that of a dolphin jumping out of the water, the flight of a bird, or the orbit of a satellite. The study of motion is kinematics, but kinematics only describes the way objects move—their velocity and acceleration. Dynamics considers the forces that affect the motion of moving objects and systems. Newton's laws of motion are the foundation of dynamics. These...
Introduction to Statistics01:17

Introduction to Statistics

The science of statistics involves collecting, analyzing, interpreting, and presenting data. The method of collecting, organizing, and summarizing data is called descriptive statistics. The systematic method of drawing inferences from the sample data and predicting unknown characteristics of a population is called inferential statistics.
In statistics, the collection of individuals or objects under study is called population. The idea of sampling is to select a portion of the larger population...
Chromatography: Introduction01:10

Chromatography: Introduction

Chromatography is a technique used to separate compounds based on differences of partitioning between two phases, the stationary phase and the mobile phase.
The phase in which the compounds linger or on which the compounds adsorb is called the stationary phase, whereas the mobile phase is the solvent that carries the solutes to be analyzed. In traditional column chromatography, the mixture flows through the stationary phase, and the compounds partition between the stationary and mobile phases...
Biostatistics: Overview01:20

Biostatistics: Overview

Biostatistics plays a crucial role in understanding and analyzing data in healthcare and biology. Biostatisticians conduct experiments, gather evidence, and draw meaningful conclusions using statistical methods and techniques. Different variables form the foundation of biostatistical analysis, allowing researchers to understand and interpret data effectively. These variables are classified into different types, each serving a specific purpose in statistical analysis.
Discrete variables are...

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Related Experiment Video

Updated: Jun 11, 2026

Micro-scale Engineering for Cell Biology
04:42

Micro-scale Engineering for Cell Biology

Published on: October 1, 2007

Introduction.

Tina L Yuan1, Lewis C Cantley

  • 1Department of Systems Biology and Beth Israel Deaconess Medical Center, Division of Signal Transduction, Harvard University, Boston, MA, 02115, USA.

Current Topics in Microbiology and Immunology
|June 29, 2010
PubMed
Summary
This summary is machine-generated.

The phosphoinositide-3-kinase (PI3K) family, conserved across species, regulates cellular order. Defects in PI3K function are linked to diseases like cancer and diabetes, highlighting the therapeutic potential of PI3K inhibitors.

Related Experiment Videos

Last Updated: Jun 11, 2026

Micro-scale Engineering for Cell Biology
04:42

Micro-scale Engineering for Cell Biology

Published on: October 1, 2007

Area of Science:

  • Biochemistry and Molecular Biology
  • Cellular Signaling
  • Evolutionary Biology

Background:

  • The phosphoinositide-3-kinase (PI3K) family of lipid kinases is evolutionarily conserved from yeast to mammals.
  • PI3Ks play a critical role in fundamental cellular processes.

Discussion:

  • PI3Ks exhibit three core properties: specific lipid substrate utilization, signaling complex nucleation at membranes, and integration of intracellular and extracellular signals.
  • These properties are essential for maintaining cellular order in a dynamic environment.

Key Insights:

  • Dysregulation of PI3K properties contributes to human diseases such as cancer and diabetes.
  • Understanding these conserved functions provides insight into disease pathogenesis.

Outlook:

  • PI3K inhibitors hold therapeutic promise for treating diseases linked to PI3K pathway defects.
  • Targeting PI3K pathways, alone or in combination, may restore cellular order in diseased tissues.