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Updated: Jun 11, 2026
04:09
Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
Gastric variceal rupture successfully treated with repeated EIS and EVL
Y Kawakami1, H Takahashi, H Mawatari
1Gastroenterology Division, Yokohama City University Graduate School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, Japan.
Hepato-Gastroenterology
|June 30, 2010
Summary
Cyanoacrylate injection effectively treated gastric variceal bleeding in a liver cirrhosis patient. This endoscopic therapy offers a viable emergency option for managing variceal rupture without a gastro-renal shunt.
Area of Science:
- Gastroenterology
- Hepatology
- Endoscopic interventions
Background:
- Liver cirrhosis frequently leads to portal hypertension and the development of gastrointestinal varices.
- Gastric variceal bleeding is a serious complication associated with significant morbidity and mortality.
Observation:
- A 68-year-old female patient with liver cirrhosis presented with severe gastrointestinal bleeding, evidenced by tarry stools.
- Upper endoscopy revealed an isolated gastric variceal rupture as the source of hemorrhage.
Findings:
- Endoscopic injection sclerotherapy using cyanoacrylate was performed on four separate occasions.
- The treatment successfully achieved hemostasis, stopping the gastric variceal bleeding.
Implications:
- Endoscopic cyanoacrylate injection is a valuable emergency treatment for gastric variceal bleeding.
- This method is particularly effective in cases without a gastro-renal shunt, offering a minimally invasive therapeutic option.
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