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Related Experiment Videos

Dural sinus occlusion: evaluation with phase-sensitive gradient-echo MR imaging.

J S Tsuruda1, A Shimakawa, N J Pelc

  • 1Department of Radiology, University of California, San Francisco 94143-0628.

AJNR. American Journal of Neuroradiology
|May 1, 1991
PubMed
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Phase-sensitive magnetic resonance imaging (MRI) combined with spin-echo MRI aids in diagnosing dural sinus thrombosis. This technique accurately identifies dural sinus occlusion and monitors treatment effectiveness.

Area of Science:

  • Radiology
  • Medical Imaging
  • Neurology

Background:

  • Dural sinus thrombosis (DST) diagnosis can be challenging.
  • Accurate assessment of venous sinus patency is crucial for effective treatment.

Purpose of the Study:

  • To evaluate the utility of limited-flip-angle, phase-sensitive velocity imaging with gradient-recalled-echo (VIGRE) MRI, combined with spin-echo MRI, for diagnosing DST.

Main Methods:

  • VIGRE sequence: rapid single-slice acquisition (50/15/2 TR/TE/excitations) with a 30-degree flip angle.
  • Four images reconstructed per slice: one magnitude and three phase-sensitive images for orthogonal motion detection.
  • Flow direction and velocity (cm/sec) derived from phase images, correlated with phantom data.

Main Results:

Related Experiment Videos

  • Normal dural sinus velocities ranged from 9.9 to 14.4 cm/sec.
  • DST diagnosis confirmed by lack of flow void (spin-echo), absence of phase shift (VIGRE), and retrograde flow (VIGRE phase image).
  • Time-of-flight angiography overestimated thrombosis extent due to spin saturation; VIGRE detected collateral flow and recanalization.

Conclusions:

  • Phase-sensitive MRI is valuable for diagnosing dural sinus occlusion.
  • VIGRE MRI effectively assesses the extent of thrombosis and monitors treatment response, including collateral formation and recanalization.