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[CKD-MBD (Chronic Kidney Disease-Mineral and Bone Disorder). KDIGO CKD-MBD Clinical Practice Guideline]

Yusuke Tsukamoto1

  • 1Division of Nephrology, Shuwa General Hospital/KDIGO.

Clinical Calcium
|June 30, 2010
PubMed

Insights

The Kidney Disease: Improving Global Outcomes (KDIGO) guideline on chronic kidney disease-mineral and bone disorder (CKD-MBD) was established in 2009. It focuses on improving patient outcomes through rigorous evidence review, representing a global collaborative effort.

Area of Science:

  • Nephrology
  • Clinical Practice Guidelines
  • Mineral and Bone Metabolism

Context:

  • The 2009 KDIGO guideline marked a significant advancement in managing chronic kidney disease-mineral and bone disorder (CKD-MBD).
  • It was developed by a global panel of experts, emphasizing international collaboration.
  • The guideline's foundation lies in a systematic review of existing evidence.

Purpose:

  • To establish evidence-based recommendations for the management of CKD-MBD.
  • To shift focus from solely improving surrogate markers to enhancing individual patient clinical outcomes.
  • To provide a framework for clinicians in treating CKD-MBD.

Summary:

  • The guideline synthesized international expertise and evidence for CKD-MBD management.
  • It introduced a novel clinical approach prioritizing patient outcomes over surrogate markers.
  • The development involved coordinated efforts from five major guideline organizations.

Impact:

  • Set a new standard for CKD-MBD care globally.
  • Influenced clinical practice and research in nephrology and bone metabolism.
  • Highlighted the importance of international collaboration in guideline development.

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