[CKD-MBD (Chronic Kidney Disease-Mineral and Bone Disorder). Effect of vitamin D on kidney and cardiovascular system]

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Updated: Jun 11, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Hideki Fujii1

  • 1Division of Nephrology and Kidney Center, Kobe University Graduate School of Medicine.

Clinical Calcium
|June 30, 2010
PubMed

Insights

Vitamin D supplementation shows promise in improving outcomes for patients with chronic kidney disease. This treatment may also protect the cardiovascular system by reducing renal injury and preventing disease progression.

Area of Science:

  • Nephrology
  • Cardiology
  • Endocrinology

Context:

  • Chronic kidney disease (CKD) is a growing global health concern.
  • CKD is associated with a significantly increased risk of cardiovascular disease (CVD).
  • Current treatments for CKD have limitations in halting disease progression and managing complications.

Purpose:

  • To explore the potential benefits of vitamin D in patients with chronic kidney disease.
  • To investigate the protective effects of vitamin D on renal and cardiovascular systems.
  • To summarize emerging evidence on vitamin D's role in managing CKD and associated CVD.

Summary:

  • Vitamin D treatment has been linked to improved outcomes in patients with chronic kidney disease (CKD).
  • Evidence suggests vitamin D may attenuate renal injury, improve renal function, and reduce proteinuria.
  • Studies indicate vitamin D may prevent atherosclerosis, vascular calcification, and left ventricular hypertrophy, protecting the cardiovascular system.

Impact:

  • Vitamin D may offer a novel therapeutic strategy for managing CKD.
  • Supplementation could potentially slow the progression of both kidney and cardiovascular diseases.
  • Further research into the mechanisms and clinical application of vitamin D in CKD is warranted.

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