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Preparation of a Corannulene-functionalized Hexahelicene by Copper(I)-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
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A cope rearrangement-based route to hexahydroazulenes

Curtis A Seizert1, Valentina D Bumbu, Vladimir B Birman

  • 1Department of Chemistry, Washington University, Campus Box 1134, One Brookings Drive, St. Louis, Missouri 63130, USA.

Organic Letters
|July 1, 2010
PubMed
Summary

2-exo-Vinyl-7-alkylidenenorbornanes undergo Cope rearrangement to form hexahydroazulene derivatives. This reaction offers a new synthetic route for complex organic molecules.

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