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Updated: Jun 11, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Adverse effects of biological agents in the treatment of psoriasis
Franco Rongioletti1, Martina Burlando, Aurora Parodi
1Clinica Dermatologica, Viale Benedetto XV 7, Genova, Italy. franco.rongioletti@unige.it
Abstract:
Tumour necrosis factor (TNF) antagonists are generally well tolerated, but carry the risk of side effects. In patients with psoriasis, the potential risks with anti-TNF agents may be overestimated because the most commonly reported adverse events are based on studies in patients with rheumatoid arthritis or inflammatory bowel disease. Whereas patients with psoriasis typically receive monotherapy, these patients are treated with biological-based combination therapies. Furthermore, patients with psoriasis have distinctive and different comorbidities, which could play a role in the development of different adverse events. However, the potential risks of the use of biological agents should always be taken into consideration.
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